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SMILES: CN(C)c1ccc(\C=C\c2ccc(OCC(CO)CF)cc2)cc1

InChI Key: InChIKey=DOBWIGMMBODBND-ONEGZZNKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370673   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50370673
PNG
(CHEMBL1169460)
Show SMILES CN(C)c1ccc(\C=C\c2ccc(OCC(CO)CF)cc2)cc1
Show InChI InChI=1S/C20H24FNO2/c1-22(2)19-9-5-16(6-10-19)3-4-17-7-11-20(12-8-17)24-15-18(13-21)14-23/h3-12,18,23H,13-15H2,1-2H3/b4-3+
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Article
PubMed
 15n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates

J Med Chem 48: 5980-8 (2005)


Article DOI: 10.1021/jm050166g
BindingDB Entry DOI: 10.7270/Q2TB17PR
More data for this
Ligand-Target Pair