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SMILES: CN(C)c1ccc(CCC(=O)c2ccccc2OCC(O)CN2CCN(CC2)c2ccccc2C)cc1

InChI Key: InChIKey=OYTSKFZAPDDTCP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370882   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50370882
PNG
(CHEMBL222351)
Show SMILES CN(C)c1ccc(CCC(=O)c2ccccc2OCC(O)CN2CCN(CC2)c2ccccc2C)cc1
Show InChI InChI=1S/C31H39N3O3/c1-24-8-4-6-10-29(24)34-20-18-33(19-21-34)22-27(35)23-37-31-11-7-5-9-28(31)30(36)17-14-25-12-15-26(16-13-25)32(2)3/h4-13,15-16,27,35H,14,17-23H2,1-3H3
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 13n/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay

J Med Chem 50: 1698-702 (2007)


Article DOI: 10.1021/jm060604z
BindingDB Entry DOI: 10.7270/Q2SB46JC
More data for this
Ligand-Target Pair