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BDBM50371130 CHEMBL390873

SMILES: OC(=O)c1ccc(cc1)C1Nc2c(F)cc(F)cc2C2C=CCC12

InChI Key: InChIKey=DQSILZGBKAYAAI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371130   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Low molecular weight phosphotyrosine protein phosphatase


(Bos taurus)		BDBM50371130
PNG
(CHEMBL390873)
Show SMILES OC(=O)c1ccc(cc1)C1Nc2c(F)cc(F)cc2C2C=CCC12 |w:19.21,23.24,9.9,c:22|
Show InChI InChI=1S/C19H15F2NO2/c20-12-8-15-13-2-1-3-14(13)17(22-18(15)16(21)9-12)10-4-6-11(7-5-10)19(23)24/h1-2,4-9,13-14,17,22H,3H2,(H,23,24)
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PC cid
PC sid
UniChem
Article
PubMed
 9.10E+5n/an/an/an/an/an/an/an/a



Institute for Research in Biomedicine (IRB)

Curated by ChEMBL


Assay Description
Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells

Eur J Med Chem 42: 1102-8 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.017
BindingDB Entry DOI: 10.7270/Q27W6D1F
More data for this
Ligand-Target Pair