BDBM50371247 CHEMBL254384

SMILES: Cc1cccc(NC(=O)c2coc(c2)-c2ccc(Cl)cc2)c1

InChI Key: InChIKey=IIFLBSPFMNFHBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50371247 (CHEMBL254384) Show SMILES Cc1cccc(NC(=O)c2coc(c2)-c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C18H14ClNO2/c1-12-3-2-4-16(9-12)20-18(21)14-10-17(22-11-14)13-5-7-15(19)8-6-13/h2-11H,1H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair