BDBM50371250 CHEMBL250876

SMILES: CN1CCc2ccc(NC(=O)c3ccc(o3)-c3ccc(Cl)cc3)cc12

InChI Key: InChIKey=GHZMGTAOVOLKRX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50371250 (CHEMBL250876) Show SMILES CN1CCc2ccc(NC(=O)c3ccc(o3)-c3ccc(Cl)cc3)cc12 Show InChI InChI=1S/C20H17ClN2O2/c1-23-11-10-13-4-7-16(12-17(13)23)22-20(24)19-9-8-18(25-19)14-2-5-15(21)6-3-14/h2-9,12H,10-11H2,1H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair