BDBM50371251 CHEMBL254382

SMILES: Cc1cccc(NC(=O)c2ccc(o2)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=TZPWIPWITVWYPT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50371251 (CHEMBL254382) Show SMILES Cc1cccc(NC(=O)c2ccc(o2)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C19H14N2O2/c1-13-4-2-7-16(10-13)21-19(22)18-9-8-17(23-18)15-6-3-5-14(11-15)12-20/h2-11H,1H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay				J Med Chem 51: 407-16 (2008) Article DOI: 10.1021/jm070637u BindingDB Entry DOI: 10.7270/Q2KK9CN7
					More data for this Ligand-Target Pair