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BDBM50371382 CHEMBL408700

SMILES: NC(=O)C(c1ccc(F)cc1)(c1cccc(F)c1)c1cccc(F)c1

InChI Key: InChIKey=CTLUQIBJZYPRJB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371382   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM50371382
PNG
(CHEMBL408700)
Show SMILES NC(=O)C(c1ccc(F)cc1)(c1cccc(F)c1)c1cccc(F)c1
Show InChI InChI=1S/C20H14F3NO/c21-16-9-7-13(8-10-16)20(19(24)25,14-3-1-5-17(22)11-14)15-4-2-6-18(23)12-15/h1-12H,(H2,24,25)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Icagen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] efflux


J Med Chem 51: 976-82 (2008)


Article DOI: 10.1021/jm070663s
BindingDB Entry DOI: 10.7270/Q23F4QGH
More data for this
Ligand-Target Pair