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SMILES: NC(=O)C(c1ccccc1)(c1cccc(F)c1)c1cccc(F)c1

InChI Key: InChIKey=WBCHZEIUTRPOCM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371383   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))		BDBM50371383
PNG
(CHEMBL261828)
Show SMILES NC(=O)C(c1ccccc1)(c1cccc(F)c1)c1cccc(F)c1
Show InChI InChI=1S/C20H15F2NO/c21-17-10-4-8-15(12-17)20(19(23)24,14-6-2-1-3-7-14)16-9-5-11-18(22)13-16/h1-13H,(H2,23,24)
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Icagen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] efflux

J Med Chem 51: 976-82 (2008)


Article DOI: 10.1021/jm070663s
BindingDB Entry DOI: 10.7270/Q23F4QGH
More data for this
Ligand-Target Pair