Found 4 hits for monomerid = 50371401 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
(RAT) | BDBM50371401
(MERIOLIN 4)Show InChI InChI=1S/C13H13N5O/c1-2-19-10-4-6-15-12-11(10)8(7-17-12)9-3-5-16-13(14)18-9/h3-7H,2H2,1H3,(H,15,17)(H2,14,16,18) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coli |
J Med Chem 51: 737-51 (2008)
Article DOI: 10.1021/jm700940h BindingDB Entry DOI: 10.7270/Q2ZP46ZR |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50371401
(MERIOLIN 4)Show InChI InChI=1S/C13H13N5O/c1-2-19-10-4-6-15-12-11(10)8(7-17-12)9-3-5-16-13(14)18-9/h3-7H,2H2,1H3,(H,15,17)(H2,14,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of recombinant GST-CDK5/p25 expressed in Escherichia coli |
J Med Chem 51: 737-51 (2008)
Article DOI: 10.1021/jm700940h BindingDB Entry DOI: 10.7270/Q2ZP46ZR |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 2 (CDK2)
(Homo sapiens (Human)) | BDBM50371401
(MERIOLIN 4)Show InChI InChI=1S/C13H13N5O/c1-2-19-10-4-6-15-12-11(10)8(7-17-12)9-3-5-16-13(14)18-9/h3-7H,2H2,1H3,(H,15,17)(H2,14,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2/cyclin A expressed in insect cells |
J Med Chem 51: 737-51 (2008)
Article DOI: 10.1021/jm700940h BindingDB Entry DOI: 10.7270/Q2ZP46ZR |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 9 (CDK9)
(Homo sapiens (Human)) | BDBM50371401
(MERIOLIN 4)Show InChI InChI=1S/C13H13N5O/c1-2-19-10-4-6-15-12-11(10)8(7-17-12)9-3-5-16-13(14)18-9/h3-7H,2H2,1H3,(H,15,17)(H2,14,16,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T expressed in insect cells |
J Med Chem 51: 737-51 (2008)
Article DOI: 10.1021/jm700940h BindingDB Entry DOI: 10.7270/Q2ZP46ZR |
More data for this Ligand-Target Pair | |