null

SMILES: CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(Cl)n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=UEGRFLJIJHRWCC-QGZVFWFLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50371484 (CHEMBL404261) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(Cl)n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C28H27ClF4N4O3S/c1-3-41(39,40)13-12-36(24(38)15-19-6-11-23(30)22(14-19)28(31,32)33)17(2)27-35-25(20-7-8-20)26(29)37(27)21-9-4-18(16-34)5-10-21/h4-6,9-11,14,17,20H,3,7-8,12-13,15H2,1-2H3/t17-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasma				Bioorg Med Chem Lett 18: 608-13 (2008) Article DOI: 10.1016/j.bmcl.2007.11.072 BindingDB Entry DOI: 10.7270/Q2668F1D
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50371484 (CHEMBL404261) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(C2CC2)c(Cl)n1-c1ccc(cc1)C#N)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C28H27ClF4N4O3S/c1-3-41(39,40)13-12-36(24(38)15-19-6-11-23(30)22(14-19)28(31,32)33)17(2)27-35-25(20-7-8-20)26(29)37(27)21-9-4-18(16-34)5-10-21/h4-6,9-11,14,17,20H,3,7-8,12-13,15H2,1-2H3/t17-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC				Bioorg Med Chem Lett 18: 608-13 (2008) Article DOI: 10.1016/j.bmcl.2007.11.072 BindingDB Entry DOI: 10.7270/Q2668F1D
					More data for this Ligand-Target Pair