null

SMILES: CCS(=O)(=O)CCN([C@H](C)c1nc(cn1-c1ccc(cc1)C#N)C1CC1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=DIIYNJJEHJXNPJ-GOSISDBHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50371510 (CHEMBL270591) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(cn1-c1ccc(cc1)C#N)C1CC1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C28H28F4N4O3S/c1-3-40(38,39)13-12-35(26(37)15-20-6-11-24(29)23(14-20)28(30,31)32)18(2)27-34-25(21-7-8-21)17-36(27)22-9-4-19(16-33)5-10-22/h4-6,9-11,14,17-18,21H,3,7-8,12-13,15H2,1-2H3/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC				Bioorg Med Chem Lett 18: 608-13 (2008) Article DOI: 10.1016/j.bmcl.2007.11.072 BindingDB Entry DOI: 10.7270/Q2668F1D
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50371510 (CHEMBL270591) Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(cn1-c1ccc(cc1)C#N)C1CC1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C28H28F4N4O3S/c1-3-40(38,39)13-12-35(26(37)15-20-6-11-24(29)23(14-20)28(30,31)32)18(2)27-34-25(21-7-8-21)17-36(27)22-9-4-19(16-33)5-10-22/h4-6,9-11,14,17-18,21H,3,7-8,12-13,15H2,1-2H3/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasma				Bioorg Med Chem Lett 18: 608-13 (2008) Article DOI: 10.1016/j.bmcl.2007.11.072 BindingDB Entry DOI: 10.7270/Q2668F1D
					More data for this Ligand-Target Pair