BDBM50371580 CHEMBL1162175
SMILES: CCNC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@H]2O[C@@H](O[C@@H]12)\C=C\c1ccccc1
InChI Key: InChIKey=NXHAXEBZOXCDKD-XIXRRVGJSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50371580 (CHEMBL1162175) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Inspire Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay | J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50371580 (CHEMBL1162175) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Inspire Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay | J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6 | |||||||||||
More data for this Ligand-Target Pair |