BDBM50371645 CHEMBL256903

SMILES: CCc1cc(no1)C(=O)NC1(CC1)C(=O)N[C@H](C)c1ncc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F

InChI Key: InChIKey=QCVMEUNDJJAUPI-GFCCVEGCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50371645 (CHEMBL256903) Show SMILES CCc1cc(no1)C(=O)NC1(CC1)C(=O)N[C@H](C)c1ncc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F Show InChI InChI=1S/C25H23Cl2F3N4O4/c1-3-15-9-19(34-38-15)23(35)33-25(4-5-25)24(36)32-12(2)21-18(28)6-13(10-31-21)16-7-14(26)8-17(27)22(16)37-11-20(29)30/h6-10,12,20H,3-5,11H2,1-2H3,(H,32,36)(H,33,35)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human bradykinin B1 receptor expressed in rat CNS				Bioorg Med Chem Lett 18: 682-7 (2008) BindingDB Entry DOI: 10.7270/Q29024NB
					More data for this Ligand-Target Pair