BDBM50371669 CHEMBL402164

SMILES: Fc1ccc(Cc2nc3CCNCCc3c(n2)-c2ccc(F)cc2)cc1

InChI Key: InChIKey=RCRKYHCZNIGMKD-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50371669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50371669 (CHEMBL402164) Show SMILES Fc1ccc(Cc2nc3CCNCCc3c(n2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C21H19F2N3/c22-16-5-1-14(2-6-16)13-20-25-19-10-12-24-11-9-18(19)21(26-20)15-3-7-17(23)8-4-15/h1-8,24H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cells				Bioorg Med Chem Lett 18: 2103-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.090 BindingDB Entry DOI: 10.7270/Q2571CW5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50371669 (CHEMBL402164) Show SMILES Fc1ccc(Cc2nc3CCNCCc3c(n2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C21H19F2N3/c22-16-5-1-14(2-6-16)13-20-25-19-10-12-24-11-9-18(19)21(26-20)15-3-7-17(23)8-4-15/h1-8,24H,9-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2B receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 2103-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.090 BindingDB Entry DOI: 10.7270/Q2571CW5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50371669 (CHEMBL402164) Show SMILES Fc1ccc(Cc2nc3CCNCCc3c(n2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C21H19F2N3/c22-16-5-1-14(2-6-16)13-20-25-19-10-12-24-11-9-18(19)21(26-20)15-3-7-17(23)8-4-15/h1-8,24H,9-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 2103-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.090 BindingDB Entry DOI: 10.7270/Q2571CW5
					More data for this Ligand-Target Pair