BDBM50371704 CHEMBL270415
SMILES: Nc1c2C(=O)c3ccccc3C(=O)c2c(Br)cc1S([O-])(=O)=O
InChI Key: InChIKey=QZZSAWGVHXXMID-UHFFFAOYSA-M
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human)) | BDBM50371704 (CHEMBL270415) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in... | J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y2 (Mus musculus) | BDBM50371704 (CHEMBL270415) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilization | Bioorg Med Chem Lett 18: 223-7 (2008) Article DOI: 10.1016/j.bmcl.2007.10.082 BindingDB Entry DOI: 10.7270/Q2RX9CXT | |||||||||||
More data for this Ligand-Target Pair |