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SMILES: C[C@H](CO)Nc1[nH]c(SCc2csc(C)n2)nc2nc(=O)sc12

InChI Key: InChIKey=KFHSDCXNOPXKDP-ZCFIWIBFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371775   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50371775
PNG
(CHEMBL402728)
Show SMILES C[C@H](CO)Nc1[nH]c(SCc2csc(C)n2)nc2nc(=O)sc12
Show InChI InChI=1S/C13H15N5O2S3/c1-6(3-19)14-10-9-11(18-13(20)23-9)17-12(16-10)22-5-8-4-21-7(2)15-8/h4,6,19H,3,5H2,1-2H3,(H2,14,16,17,18,20)/t6-/m1/s1
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n/an/a 60n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assay

Bioorg Med Chem Lett 18: 798-803 (2008)


BindingDB Entry DOI: 10.7270/Q28053GH
More data for this
Ligand-Target Pair