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SMILES: C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2n[nH]cc12

InChI Key: InChIKey=WJXFRKFRTLXOPO-MRVPVSSYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371779   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50371779
PNG
(CHEMBL257025)
Show SMILES C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2n[nH]cc12
Show InChI InChI=1S/C15H15F2N5OS/c1-8(6-23)19-13-10-5-18-22-14(10)21-15(20-13)24-7-9-3-2-4-11(16)12(9)17/h2-5,8,23H,6-7H2,1H3,(H2,18,19,20,21,22)/t8-/m1/s1
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n/an/a 220n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assay

Bioorg Med Chem Lett 18: 798-803 (2008)


BindingDB Entry DOI: 10.7270/Q28053GH
More data for this
Ligand-Target Pair