BDBM50371780 CHEMBL403656

SMILES: C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)c(cc12)C#N

InChI Key: InChIKey=LSSRJFFDFHBKHW-SECBINFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50371780 (CHEMBL403656) Show SMILES C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)c(cc12)C#N Show InChI InChI=1S/C18H15F2N5O2S/c1-9(7-26)22-15-12-5-11(6-21)17(27)23-16(12)25-18(24-15)28-8-10-3-2-4-13(19)14(10)20/h2-5,9,26H,7-8H2,1H3,(H2,22,23,24,25,27)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assay				Bioorg Med Chem Lett 18: 798-803 (2008) BindingDB Entry DOI: 10.7270/Q28053GH
					More data for this Ligand-Target Pair