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SMILES: C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nccnc12

InChI Key: InChIKey=FLYSGGFIJWABBI-SECBINFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371791   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50371791
PNG
(CHEMBL404057)
Show SMILES C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nccnc12
Show InChI InChI=1S/C16H15F2N5OS/c1-9(7-24)21-15-13-14(20-6-5-19-13)22-16(23-15)25-8-10-3-2-4-11(17)12(10)18/h2-6,9,24H,7-8H2,1H3,(H,20,21,22,23)/t9-/m1/s1
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AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assay

Bioorg Med Chem Lett 18: 798-803 (2008)


BindingDB Entry DOI: 10.7270/Q28053GH
More data for this
Ligand-Target Pair