BDBM50371922 CHEMBL402429

SMILES: CC(C)c1ccc(cc1)-c1c(-c2cc(C)no2)c(=O)[nH]c2ccc(Cl)cc12

InChI Key: InChIKey=KNOVBFWCRAKJNE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50371922 (CHEMBL402429) Show SMILES CC(C)c1ccc(cc1)-c1c(-c2cc(C)no2)c(=O)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C22H19ClN2O2/c1-12(2)14-4-6-15(7-5-14)20-17-11-16(23)8-9-18(17)24-22(26)21(20)19-10-13(3)25-27-19/h4-12H,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair