BDBM50372003 CHEMBL272707

SMILES: CC(=O)N1C2CCCC1C=C(CN1CCC(CC1)Nc1ccc3cccc(Cl)c3n1)C2

InChI Key: InChIKey=LTLQBTWXVNYQCH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50372003 (CHEMBL272707) Show SMILES CC(=O)N1C2CCCC1C=C(CN1CCC(CC1)Nc1ccc3cccc(Cl)c3n1)C2 |w:4.34,8.9,t:10,TLB:1:3:10.30.9:7.5.6| Show InChI InChI=1S/C25H31ClN4O/c1-17(31)30-21-5-3-6-22(30)15-18(14-21)16-29-12-10-20(11-13-29)27-24-9-8-19-4-2-7-23(26)25(19)28-24/h2,4,7-9,14,20-22H,3,5-6,10-13,15-16H2,1H3,(H,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	624	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Inflammation Discovery Curated by ChEMBL					Assay Description Binding affinity to CXCR3 receptor expressed in CHO cells assessed as ITAC-induced [35]GTPgammaS binding				Bioorg Med Chem Lett 18: 629-33 (2008) Article DOI: 10.1016/j.bmcl.2007.11.075 BindingDB Entry DOI: 10.7270/Q29S1RWG
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