BDBM50372073 CHEMBL256220

SMILES: CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CS(=O)(=O)NC(=O)Cc2cc(OC)ccc2OC)cc1

InChI Key: InChIKey=XVCXTZSYZRZZHF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50372073 (CHEMBL256220) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CS(=O)(=O)NC(=O)Cc2cc(OC)ccc2OC)cc1 Show InChI InChI=1S/C33H34N2O8S/c1-5-42-31-25-9-7-8-10-26(25)32(43-6-2)30-27(31)19-35(33(30)37)23-13-11-21(12-14-23)20-44(38,39)34-29(36)18-22-17-24(40-3)15-16-28(22)41-4/h7-17H,5-6,18-20H2,1-4H3,(H,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 2048-54 (2008) Article DOI: 10.1016/j.bmcl.2008.01.103 BindingDB Entry DOI: 10.7270/Q2J96770
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50372073 (CHEMBL256220) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CS(=O)(=O)NC(=O)Cc2cc(OC)ccc2OC)cc1 Show InChI InChI=1S/C33H34N2O8S/c1-5-42-31-25-9-7-8-10-26(25)32(43-6-2)30-27(31)19-35(33(30)37)23-13-11-21(12-14-23)20-44(38,39)34-29(36)18-22-17-24(40-3)15-16-28(22)41-4/h7-17H,5-6,18-20H2,1-4H3,(H,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells in presence of 10% human serum				Bioorg Med Chem Lett 18: 2048-54 (2008) Article DOI: 10.1016/j.bmcl.2008.01.103 BindingDB Entry DOI: 10.7270/Q2J96770
					More data for this Ligand-Target Pair