BDBM50372318 CHEMBL402220

SMILES: COc1ccc2[nH]c(CCN3CCC[C@H]3C)cc2c1

InChI Key: InChIKey=QGPFBJWQIPCKTR-GFCCVEGCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50372318 (CHEMBL402220) Show SMILES COc1ccc2[nH]c(CCN3CCC[C@H]3C)cc2c1 Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells				Bioorg Med Chem Lett 18: 355-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50372318 (CHEMBL402220) Show SMILES COc1ccc2[nH]c(CCN3CCC[C@H]3C)cc2c1 Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes				Bioorg Med Chem Lett 18: 355-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V
					More data for this Ligand-Target Pair