BDBM50372428 CHEMBL272615

SMILES: ONC(=O)c1cc2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2s1

InChI Key: InChIKey=FCGWIBHVSXLROC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50372428 (CHEMBL272615) Show SMILES ONC(=O)c1cc2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2s1 Show InChI InChI=1S/C19H14N2O4S2/c22-19(20-23)17-10-13-8-9-14(11-16(13)26-17)21-27(24,25)18-7-3-5-12-4-1-2-6-15(12)18/h1-11,21,23H,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of human HDAC1				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair