BDBM50372431 CHEMBL261829

SMILES: ONC(=O)c1cc2cc(NC(=O)c3cccc4ccccc34)ccc2s1

InChI Key: InChIKey=FSBZYLBTSUIPTL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50372431 (CHEMBL261829) Show SMILES ONC(=O)c1cc2cc(NC(=O)c3cccc4ccccc34)ccc2s1 Show InChI InChI=1S/C20H14N2O3S/c23-19(16-7-3-5-12-4-1-2-6-15(12)16)21-14-8-9-17-13(10-14)11-18(26-17)20(24)22-25/h1-11,25H,(H,21,23)(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of human HDAC1				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50372431 (CHEMBL261829) Show SMILES ONC(=O)c1cc2cc(NC(=O)c3cccc4ccccc34)ccc2s1 Show InChI InChI=1S/C20H14N2O3S/c23-19(16-7-3-5-12-4-1-2-6-15(12)16)21-14-8-9-17-13(10-14)11-18(26-17)20(24)22-25/h1-11,25H,(H,21,23)(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of human HDAC1				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair