BDBM50372449 CHEMBL406650

SMILES: ONC(=O)CCCCCC(=O)N(CC(=O)Nc1cccc2cccnc12)CC(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=SBMGJAVTUPAYSP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50372449 (CHEMBL406650) Show SMILES ONC(=O)CCCCCC(=O)N(CC(=O)Nc1cccc2cccnc12)CC(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C29H30N6O5/c36-24(34-40)14-2-1-3-15-27(39)35(18-25(37)32-22-12-4-8-20-10-6-16-30-28(20)22)19-26(38)33-23-13-5-9-21-11-7-17-31-29(21)23/h4-13,16-17,40H,1-3,14-15,18-19H2,(H,32,37)(H,33,38)(H,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of human HDAC1				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair