BDBM50372461 CHEMBL270887

SMILES: ONC(=O)Cc1ccc(s1)-c1csc(NC(=O)Cc2ccccc2)n1

InChI Key: InChIKey=HUJWYILIOQITFG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50372461 (CHEMBL270887) Show SMILES ONC(=O)Cc1ccc(s1)-c1csc(NC(=O)Cc2ccccc2)n1 Show InChI InChI=1S/C17H15N3O3S2/c21-15(8-11-4-2-1-3-5-11)19-17-18-13(10-24-17)14-7-6-12(25-14)9-16(22)20-23/h1-7,10,23H,8-9H2,(H,20,22)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of HDAC8				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50372461 (CHEMBL270887) Show SMILES ONC(=O)Cc1ccc(s1)-c1csc(NC(=O)Cc2ccccc2)n1 Show InChI InChI=1S/C17H15N3O3S2/c21-15(8-11-4-2-1-3-5-11)19-17-18-13(10-24-17)14-7-6-12(25-14)9-16(22)20-23/h1-7,10,23H,8-9H2,(H,20,22)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of HDAC1				J Med Chem 51: 1505-29 (2008) Article DOI: 10.1021/jm7011408 BindingDB Entry DOI: 10.7270/Q2M32WMT
					More data for this Ligand-Target Pair