BDBM50372520 CHEMBL271233

SMILES: COc1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)Nc1cccc2ccc(C)nc12

InChI Key: InChIKey=FFFWFVRMWPALDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM50372520 (CHEMBL271233) Show SMILES COc1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)Nc1cccc2ccc(C)nc12 Show InChI InChI=1S/C17H15N3O5S/c1-11-6-7-12-4-3-5-14(17(12)18-11)19-26(23,24)16-9-8-13(25-2)10-15(16)20(21)22/h3-10,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC				Bioorg Med Chem Lett 18: 329-35 (2008) Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63
					More data for this Ligand-Target Pair