BDBM50372541 CHEMBL401529

SMILES: CCOC(=O)CCN(C1CCN(CC1)c1ccncc1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=BPMZBEJQLCBOPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50372541 (CHEMBL401529) Show SMILES CCOC(=O)CCN(C1CCN(CC1)c1ccncc1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C28H32ClN3O5S/c1-2-37-28(34)11-17-32(25-9-15-31(16-10-25)24-7-13-30-14-8-24)27(33)12-18-38(35,36)26-6-4-21-19-23(29)5-3-22(21)20-26/h3-8,13-14,19-20,25H,2,9-12,15-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 16: 2243-60 (2008) Article DOI: 10.1016/j.bmc.2007.11.073 BindingDB Entry DOI: 10.7270/Q2ZC83QS
					More data for this Ligand-Target Pair