BDBM50372595 CHEMBL272436
SMILES: NC1CC(=O)N[C@@H]2CN[C@H](C2)C(=O)NC(N)=NCCC[C@H](NC(=O)CNC1=O)C(O)=O
InChI Key: InChIKey=HWQCIVMCAIEOPT-OFLUOSHYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-5 (Homo sapiens (Human)) | BDBM50372595 (CHEMBL272436) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Parma Curated by ChEMBL | Assay Description Displacement of [125I]echistatin from human integrin alpha-V-beta-5 receptor by solid phase assay | J Med Chem 51: 1771-82 (2008) Article DOI: 10.1021/jm701214z BindingDB Entry DOI: 10.7270/Q29K4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50372595 (CHEMBL272436) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Parma Curated by ChEMBL | Assay Description Displacement of [125I]echistatin from human integrin alpha-V-beta-3 receptor low affinity state by solid phase assay | J Med Chem 51: 1771-82 (2008) Article DOI: 10.1021/jm701214z BindingDB Entry DOI: 10.7270/Q29K4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50372595 (CHEMBL272436) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Parma Curated by ChEMBL | Assay Description Displacement of [125I]echistatin from human integrin alpha-V-beta-3 receptor high affinity state by solid phase assay | J Med Chem 51: 1771-82 (2008) Article DOI: 10.1021/jm701214z BindingDB Entry DOI: 10.7270/Q29K4C3P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50372595 (CHEMBL272436) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Parma Curated by ChEMBL | Assay Description Displacement of [125I]echistatin from human integrin alpha-V-beta-3 receptor by solid phase assay | J Med Chem 51: 1771-82 (2008) Article DOI: 10.1021/jm701214z BindingDB Entry DOI: 10.7270/Q29K4C3P | |||||||||||
More data for this Ligand-Target Pair |