BDBM50372832 CHEMBL272068

SMILES: Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)(C)C(O)=O

InChI Key: InChIKey=OMYKGVIQNBTKOU-FQEVSTJZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50372832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372832 (CHEMBL272068) Show SMILES Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)(C)C(O)=O Show InChI InChI=1S/C28H36FN7O3/c1-28(2,26(37)38)22-15-21(25-32-33-34-35(25)3)16-24(17-22)31-27(39)30-11-5-13-36-12-4-6-20(18-36)14-19-7-9-23(29)10-8-19/h7-10,15-17,20H,4-6,11-14,18H2,1-3H3,(H,37,38)(H2,30,31,39)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50372832 (CHEMBL272068) Show SMILES Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)(C)C(O)=O Show InChI InChI=1S/C28H36FN7O3/c1-28(2,26(37)38)22-15-21(25-32-33-34-35(25)3)16-24(17-22)31-27(39)30-11-5-13-36-12-4-6-20(18-36)14-19-7-9-23(29)10-8-19/h7-10,15-17,20H,4-6,11-14,18H2,1-3H3,(H,37,38)(H2,30,31,39)/t20-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372832 (CHEMBL272068) Show SMILES Cn1nnnc1-c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)C(C)(C)C(O)=O Show InChI InChI=1S/C28H36FN7O3/c1-28(2,26(37)38)22-15-21(25-32-33-34-35(25)3)16-24(17-22)31-27(39)30-11-5-13-36-12-4-6-20(18-36)14-19-7-9-23(29)10-8-19/h7-10,15-17,20H,4-6,11-14,18H2,1-3H3,(H,37,38)(H2,30,31,39)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.304	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxis				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair