null

SMILES: C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nccn1C

InChI Key: InChIKey=FLHWJOBAIDQWDE-FZOAFFARSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50372838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372838 (CHEMBL429323) Show SMILES C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nccn1C Show InChI InChI=1S/C27H34FN5O2/c1-19(30-27(35)31-24-7-3-6-22(17-24)26-29-12-14-32(26)2)15-25(34)33-13-4-5-21(18-33)16-20-8-10-23(28)11-9-20/h3,6-12,14,17,19,21,25,34H,4-5,13,15-16,18H2,1-2H3,(H2,30,31,35)/t19-,21+,25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxis				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50372838 (CHEMBL429323) Show SMILES C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nccn1C Show InChI InChI=1S/C27H34FN5O2/c1-19(30-27(35)31-24-7-3-6-22(17-24)26-29-12-14-32(26)2)15-25(34)33-13-4-5-21(18-33)16-20-8-10-23(28)11-9-20/h3,6-12,14,17,19,21,25,34H,4-5,13,15-16,18H2,1-2H3,(H2,30,31,35)/t19-,21+,25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372838 (CHEMBL429323) Show SMILES C[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nccn1C Show InChI InChI=1S/C27H34FN5O2/c1-19(30-27(35)31-24-7-3-6-22(17-24)26-29-12-14-32(26)2)15-25(34)33-13-4-5-21(18-33)16-20-8-10-23(28)11-9-20/h3,6-12,14,17,19,21,25,34H,4-5,13,15-16,18H2,1-2H3,(H2,30,31,35)/t19-,21+,25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair