null

SMILES: CC(C)[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C

InChI Key: InChIKey=YXGHCLLTAXLPMG-KSNOWIBYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50372849 (CHEMBL403838) Show SMILES CC(C)[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C Show InChI InChI=1S/C27H36FN7O2/c1-18(2)24(30-27(37)29-23-8-4-7-21(15-23)26-31-32-33-34(26)3)16-25(36)35-13-5-6-20(17-35)14-19-9-11-22(28)12-10-19/h4,7-12,15,18,20,24-25,36H,5-6,13-14,16-17H2,1-3H3,(H2,29,30,37)/t20-,24-,25+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372849 (CHEMBL403838) Show SMILES CC(C)[C@H](C[C@@H](O)N1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(c1)-c1nnnn1C Show InChI InChI=1S/C27H36FN7O2/c1-18(2)24(30-27(37)29-23-8-4-7-21(15-23)26-31-32-33-34(26)3)16-25(36)35-13-5-6-20(17-35)14-19-9-11-22(28)12-10-19/h4,7-12,15,18,20,24-25,36H,5-6,13-14,16-17H2,1-3H3,(H2,29,30,37)/t20-,24-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair