BDBM50372860 CHEMBL270146

SMILES: CC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C

InChI Key: InChIKey=NQAYKLXCSBWKMD-SQJMNOBHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50372860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372860 (CHEMBL270146) Show SMILES CC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C Show InChI InChI=1S/C29H40FN7O2/c1-5-25(12-14-37-13-6-7-21(19-37)15-20-8-10-24(30)11-9-20)31-28(38)32-26-17-22(27-33-34-35-36(27)4)16-23(18-26)29(2,3)39/h8-11,16-18,21,25,39H,5-7,12-15,19H2,1-4H3,(H2,31,32,38)/t21-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50372860 (CHEMBL270146) Show SMILES CC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C Show InChI InChI=1S/C29H40FN7O2/c1-5-25(12-14-37-13-6-7-21(19-37)15-20-8-10-24(30)11-9-20)31-28(38)32-26-17-22(27-33-34-35-36(27)4)16-23(18-26)29(2,3)39/h8-11,16-18,21,25,39H,5-7,12-15,19H2,1-4H3,(H2,31,32,38)/t21-,25+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50372860 (CHEMBL270146) Show SMILES CC[C@H](CCN1CCC[C@@H](Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(cc(c1)C(C)(C)O)-c1nnnn1C Show InChI InChI=1S/C29H40FN7O2/c1-5-25(12-14-37-13-6-7-21(19-37)15-20-8-10-24(30)11-9-20)31-28(38)32-26-17-22(27-33-34-35-36(27)4)16-23(18-26)29(2,3)39/h8-11,16-18,21,25,39H,5-7,12-15,19H2,1-4H3,(H2,31,32,38)/t21-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxis				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair