null

SMILES: CCN(CC)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=YWEJXMRKAAFWNX-HKBQPEDESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372917 (CHEMBL403761) Show SMILES CCN(CC)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:12| Show InChI InChI=1S/C31H39FN4O2S/c1-6-34(7-2)21-31-19-23-20-33-36(27-12-10-26(32)11-13-27)29(23)18-25(31)16-17-35(22-31)39(37,38)28-14-8-24(9-15-28)30(3,4)5/h8-15,18,20H,6-7,16-17,19,21-22H2,1-5H3/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372917 (CHEMBL403761) Show SMILES CCN(CC)C[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C |c:12| Show InChI InChI=1S/C31H39FN4O2S/c1-6-34(7-2)21-31-19-23-20-33-36(27-12-10-26(32)11-13-27)29(23)18-25(31)16-17-35(22-31)39(37,38)28-14-8-24(9-15-28)30(3,4)5/h8-15,18,20H,6-7,16-17,19,21-22H2,1-5H3/t31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair