null

SMILES: Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)Nc2ccccc2)cc1

InChI Key: InChIKey=SNMCLYVYUVDBPC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372954 (CHEMBL403178) Show SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)Nc2ccccc2)cc1 |w:6.5,c:12| Show InChI InChI=1S/C29H26F2N4O2S/c30-24-8-6-21(7-9-24)17-29-18-22-19-32-35(27-12-10-25(31)11-13-27)28(22)16-23(29)14-15-34(20-29)38(36,37)33-26-4-2-1-3-5-26/h1-13,16,19,33H,14-15,17-18,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372954 (CHEMBL403178) Show SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)Nc2ccccc2)cc1 |w:6.5,c:12| Show InChI InChI=1S/C29H26F2N4O2S/c30-24-8-6-21(7-9-24)17-29-18-22-19-32-35(27-12-10-25(31)11-13-27)28(22)16-23(29)14-15-34(20-29)38(36,37)33-26-4-2-1-3-5-26/h1-13,16,19,33H,14-15,17-18,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair