null

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CO)C1)cnn3-c1ccc(F)cc1

InChI Key: InChIKey=CIJCJPHZCXBSOM-HHHXNRCGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372978 (CHEMBL270839) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CO)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C27H30FN3O3S/c1-26(2,3)20-4-10-24(11-5-20)35(33,34)30-13-12-21-14-25-19(15-27(21,17-30)18-32)16-29-31(25)23-8-6-22(28)7-9-23/h4-11,14,16,32H,12-13,15,17-18H2,1-3H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372978 (CHEMBL270839) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(CO)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C27H30FN3O3S/c1-26(2,3)20-4-10-24(11-5-20)35(33,34)30-13-12-21-14-25-19(15-27(21,17-30)18-32)16-29-31(25)23-8-6-22(28)7-9-23/h4-11,14,16,32H,12-13,15,17-18H2,1-3H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair