BDBM50373363 CHEMBL263904

SMILES: CC(C)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1

InChI Key: InChIKey=SREDJGDTFRKPKG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50373363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50373363 (CHEMBL263904) Show SMILES CC(C)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1 Show InChI InChI=1S/C16H23ClN4OS/c1-11(2)23-16-18-13-9-12(17)15(10-14(13)19-16)21-5-3-20(4-6-21)7-8-22/h9-11,22H,3-8H2,1-2H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-NC from human ORL1 receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 18: 3278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.04.054 BindingDB Entry DOI: 10.7270/Q2HT2Q57
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50373363 (CHEMBL263904) Show SMILES CC(C)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1 Show InChI InChI=1S/C16H23ClN4OS/c1-11(2)23-16-18-13-9-12(17)15(10-14(13)19-16)21-5-3-20(4-6-21)7-8-22/h9-11,22H,3-8H2,1-2H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from human cloned kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 18: 3278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.04.054 BindingDB Entry DOI: 10.7270/Q2HT2Q57
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50373363 (CHEMBL263904) Show SMILES CC(C)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1 Show InChI InChI=1S/C16H23ClN4OS/c1-11(2)23-16-18-13-9-12(17)15(10-14(13)19-16)21-5-3-20(4-6-21)7-8-22/h9-11,22H,3-8H2,1-2H3,(H,18,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 18: 3278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.04.054 BindingDB Entry DOI: 10.7270/Q2HT2Q57
					More data for this Ligand-Target Pair