BDBM50373778 CHEMBL257902

SMILES: Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)C1C=CN=N1

InChI Key: InChIKey=FIVGKJJWXJXLRA-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50373778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50373778 (CHEMBL257902) Show SMILES Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)C1C=CN=N1 |c:32,34| Show InChI InChI=1S/C21H22N8O3/c1-27-12-13(15-4-8-23-26-15)11-16(19(27)30)24-20(31)28-9-5-14(6-10-28)29-17-3-2-7-22-18(17)25-21(29)32/h2-4,7-8,11-12,14-15H,5-6,9-10H2,1H3,(H,24,31)(H,22,25,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human recombinant CL receptor /RAMP1				Bioorg Med Chem Lett 18: 755-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.042 BindingDB Entry DOI: 10.7270/Q2T43TZ2
					More data for this Ligand-Target Pair
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50373778 (CHEMBL257902) Show SMILES Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)C1C=CN=N1 |c:32,34| Show InChI InChI=1S/C21H22N8O3/c1-27-12-13(15-4-8-23-26-15)11-16(19(27)30)24-20(31)28-9-5-14(6-10-28)29-17-3-2-7-22-18(17)25-21(29)32/h2-4,7-8,11-12,14-15H,5-6,9-10H2,1H3,(H,24,31)(H,22,25,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assay				Bioorg Med Chem Lett 18: 755-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.042 BindingDB Entry DOI: 10.7270/Q2T43TZ2
					More data for this Ligand-Target Pair
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50373778 (CHEMBL257902) Show SMILES Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)C1C=CN=N1 |c:32,34| Show InChI InChI=1S/C21H22N8O3/c1-27-12-13(15-4-8-23-26-15)11-16(19(27)30)24-20(31)28-9-5-14(6-10-28)29-17-3-2-7-22-18(17)25-21(29)32/h2-4,7-8,11-12,14-15H,5-6,9-10H2,1H3,(H,24,31)(H,22,25,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	872	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation in presence of 50% human serum by cell based ...				Bioorg Med Chem Lett 18: 755-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.042 BindingDB Entry DOI: 10.7270/Q2T43TZ2
					More data for this Ligand-Target Pair