BDBM50374049 CHEMBL257855

SMILES: Nc1ccc(cc1)-c1ccc(N)c(NC(=O)c2cccnc2)c1

InChI Key: InChIKey=UNJPNGAMBOAAEC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50374049 (CHEMBL257855) Show SMILES Nc1ccc(cc1)-c1ccc(N)c(NC(=O)c2cccnc2)c1 Show InChI InChI=1S/C18H16N4O/c19-15-6-3-12(4-7-15)13-5-8-16(20)17(10-13)22-18(23)14-2-1-9-21-11-14/h1-11H,19-20H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 18: 973-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.031 BindingDB Entry DOI: 10.7270/Q2765G5S
					More data for this Ligand-Target Pair