BDBM50374053 CHEMBL257949

SMILES: Nc1ccc(cc1NC(=O)c1cccnc1)-c1ccc(cc1)C(=O)c1ccccc1

InChI Key: InChIKey=BFMLGNUMZSMHPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50374053 (CHEMBL257949) Show SMILES Nc1ccc(cc1NC(=O)c1cccnc1)-c1ccc(cc1)C(=O)c1ccccc1 Show InChI InChI=1S/C25H19N3O2/c26-22-13-12-20(15-23(22)28-25(30)21-7-4-14-27-16-21)17-8-10-19(11-9-17)24(29)18-5-2-1-3-6-18/h1-16H,26H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 18: 973-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.031 BindingDB Entry DOI: 10.7270/Q2765G5S
					More data for this Ligand-Target Pair