BDBM50374055 CHEMBL269944

SMILES: CNC(=O)c1ccc(N)c(NC(=O)c2ccc(NC(C)=O)cc2)c1

InChI Key: InChIKey=AUSABHGFIQLYBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50374055 (CHEMBL269944) Show SMILES CNC(=O)c1ccc(N)c(NC(=O)c2ccc(NC(C)=O)cc2)c1 Show InChI InChI=1S/C17H18N4O3/c1-10(22)20-13-6-3-11(4-7-13)17(24)21-15-9-12(16(23)19-2)5-8-14(15)18/h3-9H,18H2,1-2H3,(H,19,23)(H,20,22)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 18: 973-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.031 BindingDB Entry DOI: 10.7270/Q2765G5S
					More data for this Ligand-Target Pair