BDBM50374059 CHEMBL403100

SMILES: CC(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1O)-c1ccccc1

InChI Key: InChIKey=XTYGZPBJDVNICY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50374059 (CHEMBL403100) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1O)-c1ccccc1 Show InChI InChI=1S/C21H18N2O3/c1-14(24)22-18-10-7-16(8-11-18)21(26)23-19-13-17(9-12-20(19)25)15-5-3-2-4-6-15/h2-13,25H,1H3,(H,22,24)(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 18: 973-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.031 BindingDB Entry DOI: 10.7270/Q2765G5S
					More data for this Ligand-Target Pair