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BDBM50374192 CHEMBL271866

SMILES: Oc1cccn(CS(=O)(=O)c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)c1=O

InChI Key: InChIKey=CDYLCTGLLNQEQF-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50374192
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50374192 (CHEMBL271866) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 18: 405-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.049 BindingDB Entry DOI: 10.7270/Q2T154HP
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50374192 (CHEMBL271866) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 18: 405-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.049 BindingDB Entry DOI: 10.7270/Q2T154HP
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50374192 (CHEMBL271866) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 18: 405-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.049 BindingDB Entry DOI: 10.7270/Q2T154HP
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50374192 (CHEMBL271866) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem Lett 18: 405-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.049 BindingDB Entry DOI: 10.7270/Q2T154HP
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50374192 (CHEMBL271866) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 18: 405-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.049 BindingDB Entry DOI: 10.7270/Q2T154HP
					More data for this Ligand-Target Pair