BDBM50374265 CHEMBL257862

SMILES: Fc1cc(ccc1N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O)-n1ccnc1CN1CCOCC1

InChI Key: InChIKey=ATUOWYMDQOHEOU-MKMNVTDBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50374265 (CHEMBL257862) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O)-n1ccnc1CN1CCOCC1 |w:10.11| Show InChI InChI=1S/C24H25ClFN5O4S2/c25-22-4-2-18(36-22)6-14-37(33,34)28-20-5-8-31(24(20)32)21-3-1-17(15-19(21)26)30-9-7-27-23(30)16-29-10-12-35-13-11-29/h1-4,6-7,9,14-15,20,28H,5,8,10-13,16H2/b14-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of factor 10a				Bioorg Med Chem Lett 18: 28-33 (2008) Article DOI: 10.1016/j.bmcl.2007.11.019 BindingDB Entry DOI: 10.7270/Q29024PS
					More data for this Ligand-Target Pair