BDBM50374603 CHEMBL272610::US9604926, Compound SN-48::US9724435, Compound SN-48
SMILES: O=c1oc2ccccc2n1CCCCCCN1CCN(CC1)C1CCCCC1
InChI Key: InChIKey=WPZCHALBHCESQX-UHFFFAOYSA-N
Data: 8 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sigma-2 receptor (Rattus norvegicus (Rat)) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.06 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma-2 receptor (Rattus norvegicus (Rat)) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.06 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma intracellular receptor 2 (Mus musculus (Mouse)) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.06 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by PDSP Ki Database | Assay Description Displacement of [3H](+)-pentazocine from opioid sigma1 receptor in rat brain homogenate | J Med Chem 51: 1482-6 (2008) Article DOI: 10.1021/jm701357m BindingDB Entry DOI: 10.7270/Q2736RTZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50374603 (CHEMBL272610 | US9604926, Compound SN-48 | US97244...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNIVERSITY OF MISSISSIPPI US Patent | Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ... | US Patent US9604926 (2017) BindingDB Entry DOI: 10.7270/Q27D2X6J | |||||||||||
More data for this Ligand-Target Pair |