Found 4 hits for monomerid = 50374643 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50374643
(CHEMBL272482)Show SMILES COC(=O)[C@@H]1C[C@H](OCOCC(F)(F)F)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1 Show InChI InChI=1S/C24H29F3O8/c1-22-6-4-14-21(30)35-17(13-5-7-32-10-13)9-23(14,2)19(22)18(28)16(8-15(22)20(29)31-3)34-12-33-11-24(25,26)27/h5,7,10,14-17,19H,4,6,8-9,11-12H2,1-3H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McLean Hospital
Curated by ChEMBL
| Assay Description
Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells |
Bioorg Med Chem 16: 1279-86 (2008)
Article DOI: 10.1016/j.bmc.2007.10.067
BindingDB Entry DOI: 10.7270/Q2ZK5HJF |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50374643
(CHEMBL272482)Show SMILES COC(=O)[C@@H]1C[C@H](OCOCC(F)(F)F)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1 Show InChI InChI=1S/C24H29F3O8/c1-22-6-4-14-21(30)35-17(13-5-7-32-10-13)9-23(14,2)19(22)18(28)16(8-15(22)20(29)31-3)34-12-33-11-24(25,26)27/h5,7,10,14-17,19H,4,6,8-9,11-12H2,1-3H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McLean Hospital
Curated by ChEMBL
| Assay Description
Displacement of [3H]diprenorphine from mouse delta opioid receptor expressed in CHO cells |
Bioorg Med Chem 16: 1279-86 (2008)
Article DOI: 10.1016/j.bmc.2007.10.067
BindingDB Entry DOI: 10.7270/Q2ZK5HJF |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50374643
(CHEMBL272482)Show SMILES COC(=O)[C@@H]1C[C@H](OCOCC(F)(F)F)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1 Show InChI InChI=1S/C24H29F3O8/c1-22-6-4-14-21(30)35-17(13-5-7-32-10-13)9-23(14,2)19(22)18(28)16(8-15(22)20(29)31-3)34-12-33-11-24(25,26)27/h5,7,10,14-17,19H,4,6,8-9,11-12H2,1-3H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McLean Hospital
Curated by ChEMBL
| Assay Description
Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in CHO cells |
Bioorg Med Chem 16: 1279-86 (2008)
Article DOI: 10.1016/j.bmc.2007.10.067
BindingDB Entry DOI: 10.7270/Q2ZK5HJF |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50374643
(CHEMBL272482)Show SMILES COC(=O)[C@@H]1C[C@H](OCOCC(F)(F)F)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1 Show InChI InChI=1S/C24H29F3O8/c1-22-6-4-14-21(30)35-17(13-5-7-32-10-13)9-23(14,2)19(22)18(28)16(8-15(22)20(29)31-3)34-12-33-11-24(25,26)27/h5,7,10,14-17,19H,4,6,8-9,11-12H2,1-3H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a |
McLean Hospital
Curated by ChEMBL
| Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding |
Bioorg Med Chem 16: 1279-86 (2008)
Article DOI: 10.1016/j.bmc.2007.10.067
BindingDB Entry DOI: 10.7270/Q2ZK5HJF |
More data for this
Ligand-Target Pair | |
Search and Browse
