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SMILES: CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NCC(C)(C)C

InChI Key: InChIKey=JGNZTJUQNULPSL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374690   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))		BDBM50374690
PNG
(CHEMBL271863)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NCC(C)(C)C |w:1.0|
Show InChI InChI=1S/C22H25N5O3S/c1-12-9-23-20(30)17-7-13-5-6-14(8-16(13)27(12)17)18(28)26-21-25-15(10-31-21)19(29)24-11-22(2,3)4/h5-8,10,12H,9,11H2,1-4H3,(H,23,30)(H,24,29)(H,25,26,28)
PDB
MMDB

NCI pathway
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KEGG

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Similars
Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of MK2

Bioorg Med Chem Lett 18: 938-41 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.037
BindingDB Entry DOI: 10.7270/Q22B8ZWZ
More data for this
Ligand-Target Pair