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SMILES: COc1ccc(OC2CCCN(C2=O)c2ccc(cc2F)-c2ccccc2S(C)(=O)=O)cc1

InChI Key: InChIKey=OMCCPURCGAUBPU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374872   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50374872
PNG
(CHEMBL256458)
Show SMILES COc1ccc(OC2CCCN(C2=O)c2ccc(cc2F)-c2ccccc2S(C)(=O)=O)cc1 |w:7.6|
Show InChI InChI=1S/C25H24FNO5S/c1-31-18-10-12-19(13-11-18)32-23-7-5-15-27(25(23)28)22-14-9-17(16-21(22)26)20-6-3-4-8-24(20)33(2,29)30/h3-4,6,8-14,16,23H,5,7,15H2,1-2H3
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MMDB

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 200n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 2428-33 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.054
BindingDB Entry DOI: 10.7270/Q2RX9CZ8
More data for this
Ligand-Target Pair