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SMILES: CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(N(CC(O)=O)S(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1

InChI Key: InChIKey=WFYUDPRNHZAOBW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374896   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50374896
PNG
(CHEMBL271427)
Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(N(CC(O)=O)S(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1 |w:18.19|
Show InChI InChI=1S/C30H26ClFN2O7S2/c1-42(38,39)28-7-3-2-5-24(28)21-10-13-26(25(32)17-21)33-14-4-6-27(30(33)37)34(18-29(35)36)43(40,41)23-12-9-19-15-22(31)11-8-20(19)16-23/h2-3,5,7-13,15-17,27H,4,6,14,18H2,1H3,(H,35,36)
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 1n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 2428-33 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.054
BindingDB Entry DOI: 10.7270/Q2RX9CZ8
More data for this
Ligand-Target Pair